Epidermodysplasia verruciformis-like lesions in a patient with systemic lupus erythematosus.

Sir, Epidermodysplasia verruciformis (EV) is a rare, frequently familial disease, caused by chronic infection with human papillomavirus (HPV). EV is characterized by numerous flat warts and red and brownish macules, which sometimes strongly resemble pityriasis versicolor. A high percentage of these lesions develop into squamous cell carcinomas. Lesions similar to those present in EV have been clinically and histologically reported in patients with immunosuppression. We present here a patient with systemic lupus erythematosus (SLE) and EV-like lesions associated with HPV-17 and HPV-20.